A research comparing the height of the bone after implant placement in sinus augmented Maxilla on both sides with comparisons of blood clot and Platelet Rich Fibrin

Phase 3

Completed

• Conditions: People with bilateral missing Maxillary posterior teeth

• Registration Number: CTRI/2023/08/056786
• Lead Sponsor: Bathri Elangovan

Brief Summary

A dental implant is a biocompatible material placed into or onto the jawbone for prosthetic rehabilitation of a lost tooth. The vertical and horizontal bone volume in the posterior maxilla is important for implant placement.  Ridge resorption and pneumatization of the maxillary sinus, as well as the poor quality of bone, may also make the implant rehabilitation of the posterior maxilla more challenging.  Maxillary Sinus floor augmentation is the process in which the bone height and width is increased in order to stabilize the implant.  Sinus floor can be augmented with or without the use of any grafts. PRF is considered a second-generation platelet concentrate because the natural concentrate is a product without any anticoagulants.  If grafts are not used, the blood clot formed under the lifted maxillary sinus Schneiderian membrane appears to be critical importance in bone neoformation potential.  The purpose of the study is to compare the vertical bone gain, bone density and probing depth of simultaneously placed implants in sinus augmented ridges with blood clot alone versus platelet rich fibrin (PRF).

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-09
• Study Completion: 2025-05-15
• Last Update Posted: 2025-06-16

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• Patient aged more than 18 years.
• Patient with severe atrophy of the posterior maxilla with 4-6 mm of residual bone height.
• Patient with a need for implant therapy in the bilateral posterior maxillary region.
• Patient coming under the category of ASA I.
• Patient with pathology-free sinus.
• Patient being without active periodontal diseases.

Exclusion Criteria

• Patient with systemic disease/condition that might interfere with implant placement.
• Patient with active periodontal infection.
• Patient with history of parafunctional habits.
• Patient with habit of chronic smoking Patient with habit of chronic alcoholics.
• Patient undergoing corticosteroid therapy, chemotherapy, radiotherapy.
• Pregnant females.
• Patient with lack of stable posterior occlusion.
• Patient with a history of maxillary sinus pathologic features and/or surgery.
• Patient coming under the category of ASA II, III, IV.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
simultaneous implant placement.	6, 9 month
Researcher will come to know whether blood clot alone provides better bone gain when	6, 9 month
compared with Platelet Rich Fibrin (PRF) after maxillary sinus augmentation with	6, 9 month

Secondary Outcome Measures

Name	Time	Method
Researcher will come to know whether blood clot alone provides better bone density when compared with Platelet Rich Fibrin (PRF) after maxillary sinus augmentation with	simultaneous implant placement.

Trial Locations

Locations (1)

Government Dental College, Raipur; 🇮🇳 Raipur, CHHATTISGARH, India

Government Dental College, Raipur

🇮🇳Raipur, CHHATTISGARH, India

Dr Bathri Elangovan

Principal investigator

8870908165

ebathri@gmail.com