Non-invasive Phrenic Nerve Stimulation in ARDS Patient

Not Applicable

Recruiting

• Conditions: ARDS, Human; Ventilator-Induced Lung Injury; Diaphragm Injury

• Registration Number: NCT06572280
• Lead Sponsor: Southeast University, China

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-14
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Adult ARDS patients undergoing controlled mechanical ventilation<br><br> 2. The duration of endotracheal intubation < 48 hrs<br><br>Exclusion Criteria:<br><br> 1. Neurological condition affecting motor neuron or muscle (e.g. ALS)<br><br> 2. Paralysis of the phrenic nerve<br><br> 3. Proven or suspected spinal cord injury<br><br> 4. Conditions that limit diaphragm movement<br><br> 5. Patients with Implanted cardiac support systems (pacemaker, implanted defibrillator)<br><br> 6. Patients with implanted medical pumps<br><br> 7. Pregnancy<br><br> 8. Patients with skin lesions, infections or strictures in throat/neck area<br><br> 9. Patients with metallic implants<br><br> 10. Refusal to sign informed consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of enough Tidal volume;The speed of successful non-invasive electrical stimulation deployment

Secondary Outcome Measures

Name	Time	Method
Driving pressure;Diaphragm thickening fraction;Diaphragm excursion;Maximal inspiratory pressure (MIP);ventilation distribution;Respiratory system compliance