Comparison of patient state index and bispectral index for sevoflurane consumption and end tidal sevoflurane consumption in patients undergoing laparoscopic surgical and gynaecological procedures
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To determine the volume of sevoflurane consumed (in ml) in patients, while monitoring depth of anaesthesia using Bispectral Index versus Patient State Index
研究概览
简要总结
Accurate monitoring of anaesthetic depth is essential for optimizing drug delivery, ensuring patient
safety, preventing awareness during anaesthesia and enhancing recovery outcomes and reducing cost during surgical
procedures. In laparoscopic surgical and gynaecological procedures , where optimal anaesthetic dose and rapid
emergence are desirable, the use of brain-function monitors can guide more precise titration of
volatile anaesthetic agents such as sevoflurane.This achieves more significance in ASA 3 and 4 patients where
optimal anesthetic dose will reduce adverse effects.
Two widely used parameters - the Bispectral Index (BIS) and the **Patient State Index (PSI)-**offer real-time
assessment of a patient’s level of consciousness based on processed EEG data. While both aim to
prevent intraoperative awareness and reduce anaesthetic consumption, they rely on different proprietary algorithms
and EEG interpretations. BIS analyzes EEG bispectral and power spectral data, while PSI incorporates bilateral EEG
coherence and anterior-posterior phase relationships.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1-2 Scheduled for Laparoscopic gynaecological/surgical procedures.
排除标准
- •Known neurological disorders combined regional- general anaesthesia pregnant or lactating women Patient refusal.
结局指标
主要结局
To determine the volume of sevoflurane consumed (in ml) in patients, while monitoring depth of anaesthesia using Bispectral Index versus Patient State Index
时间窗: Baseline- Time of intubation,5mins,10mins,15mins,20mins,25mins,30mins,35 mins,40mins,45 mins,50mins,55mins,60mins | Post one hour of intubation -every 15mins till the end of surgery
次要结局
- -To assess the end-tidal sevoflurane concentration (ETSevo) during surgery in both groups(-To compare recovery profiles including time to extubation & response to verbal commands between the two groups.)
研究者
Dr Rangalakshmi S
RajaRajeswari Medical College and Hospital 202 Kambipura Mysore Road Bangalore