Comparison of Bispectral Index (BIS)-guided vs Clinically guided propofol induction in Adult Patients undergoing Elective Surgery under General Anaesthesia: A Prospective Randomised Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To evaluate and compare the effectiveness of BIS guided vs clinical guided anaesthesia induction by measuring propofol requirement
研究概览
简要总结
The aim of my study is to evaluate the effectiveness and safety of clinical vs BIS guided anesthesia induction using propofol infusion The study aims is to give the correct dose of propofol which improves the hemodynamic profile of the patients , increase the post op recovery .
•In OT, Baseline parameters NIBP, HR, ECG, SpO2 noted Preoxygenation by 100 percent O2 followed by IV Fentanyl 2 mcg/kg
•In Group B, infusion at 30 mg/kg/hr till BIS 50 ± 2
•In Group C, Propofol infusion at 30 mg/kg/hr till loss of verbal reflex
Atracurium 0.5 mg/kg , Endo Tracheal Intubation. Hemodynamic parameters and speed of anaesthesia induction to be recorded
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient ready to give informed written consent Men and women aged 18 years and older ASA physical status class I to III Patient coming for elective surgery under general anaesthesia.
排除标准
- •Pregnant female Lactating mother Baseline BP and/or HR fall greater than 20% on induction Emergency surgeries.
结局指标
主要结局
To evaluate and compare the effectiveness of BIS guided vs clinical guided anaesthesia induction by measuring propofol requirement
时间窗: Induction time
次要结局
- To evaluate the safety profile of BIS guided vs clinical guided anaesthesia induction by measuring hemodynamic parameters(Induction time)
研究者
PRAMEELA
AIIMS RAJKOT