A comparative study to evaluate the clinical efficacy of autologous platelets rich fibrin on chronic pain management of musculoskeletal injuries.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To assess clinical recovery by VAS score in assessment of local pain before and after PRF injection.
研究概览
简要总结
We intend to undertake the study to evaluate and compare the clinical efficacy of platelet rich fibrin (PRF) in pain management of musculoskeletal injuries. The primary objective of study is to assess the clinical recovery by VAS score in assessment of local pain before and after PRF injection. The total of 40 patients of age group equal or more than 18 years of either sex with ASA grade 1 and 2 suffering from chronic pain due to musculoskeletal injuries for atleast 3 months and patients will be followed further beyond study period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients of age group equal or more than 18 years of either sex with ASA grade 1 and
- •2.Patient suffering from chronic pain due to musculoskeletal injuries for atleast 3 months .
- •3.Patient having VAS score more than 5 without satisfactory pain relief from standard treatment.
- •4.Patient who have not received any local injectables like corticosteroids presenting to the pain clinic OPD.
排除标准
- •History of previous local anaesthetic infiltration.
- •Malignancy.
- •Active local infection/skin infection
- •Patients on anticoagulant, antiplatelet drugs, bleeding disorders
- •Patient on immunosuppressants/steroids
- •Diabetic mellitus
- •Unwillingness to participate
- •Patients on treatment for psychiatric illness
- •Pregnant and lactating women will be excluded from the study.
结局指标
主要结局
To assess clinical recovery by VAS score in assessment of local pain before and after PRF injection.
时间窗: To assess clinical recovery by VAS score in assessment of local pain at intervals of baseline,2 weeks, 4 weeks, 8 weeks and 3 months.
次要结局
- Requirement of rescue analgesia (Tramadol)(3 months)
研究者
Dr Rajmala Jaiswal
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Science.