Comparing the efficacy of Buprenorphine and Clonidine when combined with Ropivacaine in spinal anesthesia of leg surgeries.
Phase 1
Completed
- Conditions
- Health Condition 1: M80-M85- Disorders of bone density and structure
- Registration Number
- CTRI/2020/02/023197
- Lead Sponsor
- Vasanth D
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
Patients undergoing elective upper limb surgeries
American Society of Anaesthesiologist I or II
Exclusion Criteria
Patient refusal.
Allergic to opioids/ local anaesthetics.
Height < 140 cm , BMI > 30
Patient with recent history of CVA.
Coagulation disorder.
Severe CVS abnormalities.
Poorly controlled hypertension.
Poorly controlled Diabetes mellitus.
Emergency orthopaedic surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare duration of analgesia of Ropivacaine, Buprenorphine with ropivacaine, Clonidine with ropivacaine given intrathecally in terms of first <br/ ><br>rescue analgesia requirementTimepoint: Post operative period
- Secondary Outcome Measures
Name Time Method Time taken for onset of sensory and motor blockade. <br/ ><br>Intra operative haemodynamic changes. <br/ ><br>To determine the quality of analgesia and post operative analgesic first requiredTimepoint: Intra operative period and post operative periods