Phenotypic characterization of neuropsychologic and physical performance in geriatric patients suffering from hyponatremia

Recruiting

Conditions: E87.1
Hypo-osmolality and hyponatraemia

Registration Number: DRKS00005776

Lead Sponsor: niversität zu Köln

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 150

Inclusion Criteria

1. Men and women = 70 years of age with serum sodium of 130 mmol/l or below at time of admission to hospital.

Exclusion Criteria

1. Absent informed consent
2. Treatment in intensive care unit.
Specific handicaps that might limit a patient’s capability to perform one or more single tests (e.g. amputation in physical testing) do not lead to general exclusion.

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Test at admission to hospital:<br>1. Barthel Katz Index (evaluation of activity of daily living)<br>2. Mini Mental State Test (Check on cognitive impairment, 30 questions)<br>3. DemTec (identify patients with cognitive impairment, dementia)<br>4. Clock Test (screening tool for perceptual disorders and cognitive impairment)<br>5. Geriatrische Depressions-Skala (15 questions regarding activity, mood, memory and humour)<br>6. Tinetti Test (check for individual impairments of mobility, balance and physical stability)<br>7. TUG (timed up-and-go Test) (check for basic mobility and walking speed)<br>8. Esslinger Transfer Scale (check for the grade of assistance they need in transferring from bed to chair and upright standing)<br>9. Handgrip Test (screen for malnutrition and sarcopenia)<br>10. Mini Nutritional Assessment (MNA) (identifying malnourished elderly patients)<br><br>Follow-up after 14 or 21 days.

Secondary Outcome Measures

Name	Time	Method
Collection of following laboratory parameters within routine diagnostic at time of admission and after 14 or 21 days:<br>-Serum sodium<br>-Serum kalium<br>-Serum osmolarity<br>-Serum creatinine<br>-Serum urea<br>-Serum uric acid<br>-Blood analysis<br>-Serum ferritine<br>-Serum-CRP<br>-Serum iron<br>-Serum transferrin saturation<br>-Urin sodium<br>-Urin kalium<br>-Urin osmolarity<br>-Urin creatinine<br>-Urin urea<br>-Urin uric acid<br>