Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates
- Conditions
- Postoperative ComplicationsPneumoniaPostoperative Wound Infection
- Interventions
- Drug: deep neuromuscular block
- Registration Number
- NCT03174223
- Lead Sponsor
- Leiden University Medical Center
- Brief Summary
Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries. It is however unknown if the application of deep NMB leads to favourable outcome, such as lower rate of postoperative complications in general and surgical infections in specific and ultimately lower readmission rates. In the leiden university medical center, deep NMB is routinely applied for a variety of procedures, most notably laparoscopic abdominal and retroperitoneal surgery, eye surgery and neuro radiologic intervention surgery, since 2014. This retrospective study intends to investigate whether the application of deep NMB for these procedures affects patient outcome and readmission rates.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 460
- deep neuromuscular block
- moderate neuromuscular block
- general anesthesia
- complete anesthesia chart
- incomplete anesthesia chart
- missing data regarding postoperative complications or readmission
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Deep neuromuscular block deep neuromuscular block patients received a continuous rocuronium dose to maintain a depth of neuromuscular block of 1-2 twitches post tetanic count
- Primary Outcome Measures
Name Time Method Readmission 30 days after surgery readmission to the hospital
- Secondary Outcome Measures
Name Time Method Cost 30 days after surgery The total cost, including sugammadex use and readmission cost
Trial Locations
- Locations (1)
Leiden University Medical Center
🇳🇱Leiden, Netherlands