Adjuvant ketogenic diet and metastatic colorectal cancer
Phase 3
Recruiting
- Conditions
- Colon cancer.Malignant neoplasm of colon
- Registration Number
- IRCT20210919052515N2
- Lead Sponsor
- Oroumia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
Patients with stage 4 of colorectal cancer
Age over 18 years
Exclusion Criteria
Lipid metabolism disorders such as carnitine deficiency
Patients with liver failure
Metastasis to more than 50% in liver tissue
History of gastric and pancreatic surgeries
Renal cell carcinoma
Type 1 diabetes
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response to treatment including primary tumor and metastasis size before and after the intervention. Timepoint: Before and three months after the intervention. Method of measurement: With CT scan imaging in millimeters.
- Secondary Outcome Measures
Name Time Method Ketone body. Timepoint: Before and three months after the intervention. Method of measurement: Ketone meter in blood serum (mM/L).;Carcinoembryonic antigen (CEA). Timepoint: Before and three months after the intervention. Method of measurement: ELISA test (ng/mL).;Vascular endothelium growth factor expression (VEGF). Timepoint: Before and three months after the intervention. Method of measurement: Blood serum (Pg/mL).;C-Reactive Protein (CRP). Timepoint: Before and three months after the intervention. Method of measurement: Blood serum (mg/L).