Comparison of the analgesic effect of Magnesium-sulfate and Paracetamol with Paracetamol and Placebo in the treatment of renal colic

Phase 3

Recruiting

• Conditions: Renal colic.; Unspecified renal colic

• Registration Number: IRCT20190907044717N1
• Lead Sponsor: Hamedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Individuals who are clinically suspected of having renal colic or have been diagnosed with ultrasound or CT scan with a definitive diagnosis of renal colic
Minimum score of 5 from the visual analogue scale(VAS) at baseline
Glasgow Coma Scale(GCS) of 15

Exclusion Criteria

Body temperature > 38° C
Pregnancy or any doubt about pregnancy
Use of pain medication during the last 6 hours
Abdominal pain and the possibility of peritonitis
Not signing the informed consent
Unstable clinical conditions and hypotension(systolic pressure less than 90 or 20% of baseline pressure) and bradycardia(less than 60) and respiratory rate lower than 16
Disposal of stone(s)
History of heart diseases
History of liver diseases
History of kidney diseases
History of metabolic diseases
History of seizures
Drug history of calcium channel blockers
History of alcoholism
History of mental disorders, depression and recent use of sedative or anti-psychotic or antidepressants
History of drug abuse and addiction
History of neuro-muscular disease and underlying bradycardia (heart rate less than 60) and long QRS interval
History of hypotension
History of hypocalcemia and hypomagnesemia
Barbiturates and general anesthetics use

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of renal colic's pain. Timepoint: Before the intervention and 20, 40, and 60 minutes after the intervention. Method of measurement: Visual Analog Scale (VAS).