Inter-rater and Intra-rater Reliability of the Global Eyebrow Assessment Scale

Completed

• Conditions: Healthy Volunteers
• Interventions: Drug: No Intervention

• Registration Number: NCT01412086
• Lead Sponsor: Allergan

Brief Summary

This study evaluated the inter- and intra-rater reliability of the GEBA Scale with photonumeric guide for the assessment of overall eyebrow fullness. There is no treatment (intervention) associated with this study.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-08
• Study First Submitted: 2011-08-05
• Study First Submitted QC: 2011-08-08
• Study First Posted: 2011-08-09
• Primary Completion: 2011-09
• Study Completion: 2011-09
• Status Verified: 2012-09
• Results First Submitted: 2012-09-27
• Results First Submitted QC: 2012-09-27
• Last Update Submitted: 2012-09-27
• Results First Posted: 2012-10-29
• Last Update Posted: 2012-10-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

• Willing to remove makeup and jewelry at each visit
• Willing to have photographs taken of the facial area

Exclusion Criteria

• Permanent eyebrow makeup (i.e., tattooing) or eyebrow implants of any kind
• Eyebrow extension application within 3 months of study entry
• Eyebrow tint or dye application within 2 months of study entry
• Eyebrow grooming (i.e., tweezing, waxing, or threading) between visits that is not part of the current routine

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
All Participants	No Intervention	Healthy volunteers. No treatment (intervention) was received.

Primary Outcome Measures

Name	Time	Method
Inter-rater Reliability of Physician Raters Using the Global Eyebrow Assessment (GEBA) Scale	Day 1	Inter-rater agreement (among raters) of the GEBA scores (1=very sparse, 2=sparse, 3=full, 4=very full) to assess eyebrow fullness was evaluated using Kendall's coefficient of concordance (Kendall's W). Each of 7 raters scored 112 subjects' eyebrows using the GEBA Scale at 2 different time points at day 1. The overall inter-rater agreement for Kendall's W for all raters combined was estimated based on the average of the scores from those 2 different time points. The degree of agreement of the point estimates of Kendall's W was interpreted according to the reference range scale that was pre-defined as: ≤ 0: poor, 0.00-0.20: slightly, 0.21-0.40: fair, 0.41-0.60: moderate, 0.61-0.80: substantial and 0.81-1:00: almost perfect. The 95% confidence interval for Kendall's W was provided.
Intra-rater Reliability of Physician Raters Using the Global Eyebrow Assessment (GEBA) Scale	Day 1	Intra-rater (within raters) agreement of the GEBA scores (1=very sparse, 2=sparse, 3=full, 4=very full) to assess eyebrow fullness was evaluated by weighted Kappa statistics. Weighted Kappa statistics were calculated for each of 7 raters who evaluated 112 subjects using GEBA scale, assessing agreement between 2 different time points at day 1. The overall intra-rater agreement for Kappa statistics for all raters combined was estimated by pooling Kappa statistics for each rater using a chi-square statistic. The degree of agreement of the point estimates of Kappa statistics was interpreted according to the reference range scale that was predefined as: ≤ 0: poor, 0.00-0.20: slightly, 0.21-0.40: fair, 0.41-0.60: moderate, 0.61-0.80: substantial and 0.81-1:00: almost perfect. The 95% confidence interval for Kappa statistics was provided.