Relationship between brain structure and function of very preterm infants to predict neurodevelopmental outcome

Not Applicable

Completed

• Conditions: Brain development in preterm infants; Prematurity; Prediction of Cerebral PalsyMotor outcomes; Prediction of Cerebral Palsy; Motor outcomes; Neurological - Other neurological disorders; Reproductive Health and Childbirth - Complications of newborn

• Registration Number: ACTRN12613000280707
• Lead Sponsor: Professor Paul Colditz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-03-08
• Study Completion: 2016-04-21
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 119

Inclusion Criteria

Infants born at less than 30 weeks gestational age
English speaking family
Live within 200km of the Royal Brisbane and Women's Hospital
Have no congenital or chromosomal abnormality that would impact their development

Exclusion Criteria

Infants born at greater than 30 weeks gestational age
Non English-speaking family
Live >200km from the Royal Brisbane and Women's Hospital
Have a congenital or chromosomal abnormality that would impact their development

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain neuroimaging <br>Structural and diffusion imaging analyses will be performed, including high angular resolution diffusion imaging (HARDI). This will examine both the structural integrity, and structural connectivity of the brain. These data will be related to outcome at 12 months corrected age (CP/not CP)[ An MRI will be performed at 30 weeks and 40 weeks post menstrual ages (PMA).]