Survival and Predictive Factors of Clinical Outcome in Patients With Acquired Brain Injury
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acquired Brain Injury
- Sponsor
- Charles University, Czech Republic
- Enrollment
- 211
- Locations
- 1
- Primary Endpoint
- Level of consciousness achieved
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The prediction of the final neurological and functional status of patients with acquired brain injury remains very uncertain despite the findings of current medicine. The aim of the study is to evaluate the clinical outcomes in patients with the most severe degree of brain injury hospitalized in the long-term intensive care unit of the Military University Hospital Prague.
Detailed Description
The prediction of the final neurological and functional status of patients with acquired brain injury remains very uncertain despite the findings of current medicine. Current medical knowledge is particularly limited in patients with the most severe brain injury who had to be tracheostomized and admitted to long-term intensive care unit. In the Czech Republic, there is a complete lack of data on clinical outcomes in these patients. Some recent studies has not confirmed the long-standing better outcome in patients with traumatic brain injury compared to non-traumatic etiologies. The aim of the study is to evaluate the clinical outcomes in patients with the most severe degree of brain injury hospitalized in the long-term intensive care unit of the Military University Hospital Prague.
Investigators
Michal Soták
Principal Investigator
Charles University, Czech Republic
Eligibility Criteria
Inclusion Criteria
- •Acquired brain injury
- •Initial Glasgow Coma Scale (GCS) score less than 8 points
- •Tracheostomy for persistent impairment of consciousness
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Level of consciousness achieved
Time Frame: three months
Initial Glasgow coma scale (GCS) and GCS at discharge. Minimal points 3, maximal point 15. The higher the score the better the outcome.
Level of self-sufficiency
Time Frame: three months
Initial level of self-sufficiency and self-sufficiency at discharge using Barthel score. 0-100 points. A patient scoring 100 points is continent, feeds himself, dresses himself, gets up out of bed and chairs, bathes himself, walks at least a block, and can ascend and descend stairs. A score of 0 means that the patient does not meet any of the activities described above.
Secondary Outcomes
- Length of survival after discharge from intensive care.(three months)