Factors Associated With Neurological Prognosis 30 Days After an ICU Admission for a Myocardial Infarction Complicated by an Out-of-Hospital Cardiac Arrest : an Observationnal Multicentric Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Out-Of-Hospital Cardiac Arrest
- Sponsor
- Central Hospital, Nancy, France
- Enrollment
- 110
- Primary Endpoint
- Neurologic outcome (CPC)
- Last Updated
- 5 years ago
Overview
Brief Summary
This study evaluate the association of some in-ICU factors with the neurological prognosis of patients admitted for an out-of-hospital cardiac arrest due to a myocardial infarction.
Detailed Description
Pre-hospital factors associated with poor neurologic outcome are well known. Meanwhile, in-ICU factors for the first 24 hours may impact neurologic outcome. This observational study aim to study the factors such as ECLS, NSE dosage, therapeutic hypotermia... and their association with neurologic outcome in patient with myocardial infarction due to instable coronaropathy complicated by an out-of-+hospital cardiac arrest. This is designed to be a observationnal, prospective, multicentric national french study
Investigators
Pr Bruno LEVY
Professor Bruno LEVY
Central Hospital, Nancy, France
Eligibility Criteria
Inclusion Criteria
- •aged of 18 years old or more
- •non opposition of the patient, or his family if he is unable to consent, after loyal and comprehensive explanation
- •patient admitted in ICU
- •the reason for admission is a resurected out-of-hospital cardiac arrest
- •the cause of the cardiac arrest is a type 1 myocardial infarction
Exclusion Criteria
- •refractory cardiac arrest (no flow \> 30 minutes in normothermia)
- •in-hospital cardiac arrest
- •pregnancy
- •patient under juridic protection
- •opposition of the patient, or of his family is he is unable to consent.
Outcomes
Primary Outcomes
Neurologic outcome (CPC)
Time Frame: 30 day from in-ICU admission
Cerebral Performance Category Scale to assess neurologic outcome 1-2 : good outcome 3-4-5 : bad outcome
Secondary Outcomes
- Neurologic outcome (Rankin)(30 day from in-ICU admission)
- death(30 day form in-ICU admission)