临床试验/NCT01463995

NCT01463995已完成不适用

Prognosis in Neurological Intensive Care Unit Patients (proNICU Cohort)

Charite University, Berlin, Germany1 个研究点分布在 1 个国家目标入组 46 人开始时间: 2012年6月最近更新: 2018年11月29日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Charite University, Berlin, Germany
入组人数: 46
试验地点: 1
主要终点: Predictive properties of immune parameters (IL6, IL10, mHLA-DR) for functional outcome one year after symptom onset

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study examines the prognostic properties of immune parameters, clinical scores, electrophysiological tests (eeg, ssep, emg, eng) and functional imaging for the prediction of functional outcome one year after treatment on a neurological intensive care unit.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•severe neurological disease making treatment on a neurological intensive care unit necessary
•consent by the patient or the legal representative

排除标准

•participation in an interventional trial

结局指标

主要结局

Predictive properties of immune parameters (IL6, IL10, mHLA-DR) for functional outcome one year after symptom onset

时间窗: one year after symptom onset

To evaluate of the predictive properties of immune parameters (IL6, IL10, mHLA-DR) for functional outcome one year after symptom onset

次要结局

Predictive properties of immune parameters in the cerebrovascular fluid for functional outcome one year after symptom onset(one year after symptom onset)
To evaluate of the predictive properties of clinical scores for functional outcome one year after symptom onset(one year after symptom onset)
To evaluate of the predictive properties of conventional (DTI) and functional imaging (resting state) one year after symptom onset(one year after symptom onset)
To evaluate of the predictive properties of electrophysiological measurements one year after symptom onset(one year after symptom onset)
Quality of life and the occurence of depression and burnout syndrome in relatives(one year after symptom onset)
Transcriptome analyses(one year after symptom onset)
Quality of life and occurence of depression in patients one year after symptom onset(one year after symptom onset)

研究者

发起方

Charite University, Berlin, Germany

申办方类型

Other

责任方

Principal Investigator

主要研究者

Andreas Meisel

Prof. Dr. med. Andreas Meisel

Charite University, Berlin, Germany

研究点 (1)

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