The role of the glymphatic system in the development of vasospams and chronic headache after subarachnoid hemorrhage (SAH)
Recruiting
- Conditions
- chronic headache after subarachnoid hemorrhagetension headache
- Registration Number
- DRKS00031132
- Lead Sponsor
- Sektion Neurologische Schmerzforschung und -therapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
>18 years
- Consent to participate in the study by patient or authorized person.
- Aneurysmal SAB before >12 <36 months OR diagnosis of tension headache according to International Classification of Headache Disorders (ICHD-3) diagnostic criteria OR no relevant previous disease.
Exclusion Criteria
-Relevant co-morbidities (especially dementia; headache illnesses in the medical history; brain tumor; inflammatory illnesses of the central nervous system).
- Limited ability to communicate (e.g., due to language barrier or cognitive impairment)
- Pregnancy, breastfeeding
- MRI contraindications
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method quantitative measure of the glymphatic flow (due to MR-imaging)
- Secondary Outcome Measures
Name Time Method genetic analysis of Aquaporin-4 regarding single nucleotide polymorphisms (SNPs)