Effects of combination of lipoic acid and pyridoxine on albuminuria, serum advanced glycated end products and vascular inflammatory factors in patients with diabetic nephropathy

Not Applicable

• Conditions: Diabetic Nephropathy.; Glomerular disorders in diabetes mellitus; N08.3*

• Registration Number: IRCT138808252716N1
• Lead Sponsor: ational Nutrition and Food Technology Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

Inclusion Criteria: Presence of Diabetic Nephropathy

Exclusion Criteria

Chronic kidney disease, Infections, Inflammatory diseases, Receiving anti-inflammatory drugs, Vitamins B6, E, C, and Lipoic acid supplement

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Microalbuminuria. Timepoint: Baseline and Week 12. Method of measurement: ELISA.

Secondary Outcome Measures

Name	Time	Method
Hb A1c. Timepoint: Baseline and Week 12. Method of measurement: Ion Exchange Chromatography.;Serum MDA, NO, Glucose. Timepoint: Baseline and Week12. Method of measurement: Colorimetry.;Systolic and diastolic blood pressure. Timepoint: Baseline and Week 12. Method of measurement: Mercury Sphygmomanometer.;Serum pentosidine, carboxymethyl lysine, hs-CRP, IL-6, sICAM-1, sVCAM-1, sE-selectin, Endothelin-1. Timepoint: Baseline and Week12. Method of measurement: ELISA.