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Clinical Trials/NCT06544811
NCT06544811
Recruiting
N/A

Randomized Clinical Trial of A Culturally Aligned Digital Smoking Cessation Resource for American Indian Persons

Masonic Cancer Center, University of Minnesota1 site in 1 country416 target enrollmentApril 14, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Smoking Cessation
Sponsor
Masonic Cancer Center, University of Minnesota
Enrollment
416
Locations
1
Primary Endpoint
Percent of participants that are biochemically confirmed 7-day abstinence from from all combustible tobacco products with a negative breath CO test
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.

Detailed Description

This is a two-arm, parallel group, randomized controlled clinical trial. Eligible participants (n=416) will be randomized to either the culturally aligned resource or the general audience version. Participants will use the assigned resource for 6 months, and partake in surveys at baseline, and 1, 3 and 6 months, during which they will be asked several questions related to use of their assigned resource, and smoking behavior. Carbon monoxide (CO) in exhaled breath will be collected at 1, 3 and 6 months using iCO™ Smokerlyzer® (https://www.icoquit.com/us/).

Registry
clinicaltrials.gov
Start Date
April 14, 2025
End Date
October 1, 2029
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • AI race based on self-report;
  • ≥ 18 years of age via photo ID confirmation;
  • Average smoked cigarettes per day, ≥ 3 in the past 30 days;
  • considering or willing to make a quit attempt;
  • self-report having daily access to their own iPhone/Android smartphone or tablet that allows for messaging use;
  • able to read and speak English.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Percent of participants that are biochemically confirmed 7-day abstinence from from all combustible tobacco products with a negative breath CO test

Time Frame: 6 months

Percent of participants that are biochemically confirmed 7-day abstinence from all combustible tobacco products (defined as self-reported abstinence during the past seven days \[not even a puff of cigarettes, cigars, hookah, or pipe tobacco\] with a negative breath CO test ≤ 4 ppm).

Secondary Outcomes

  • Percent of participants that are biochemically-confirmed 7-day abstinence(1 and 3 months)
  • Percent of participants that self-report 24-hour abstinence(1, 3, and 6 months)
  • Percent of participants that self-report 7-day abstinence(1, 3, and 6 months)
  • Percent of participants that self-report 30-day abstinence(3 and 6 months)
  • Mean cigarettes per day in past 7 days(1, 3, and 6 months)
  • Number of 24-hour quit attempts in past 30 days(1, 3, and 6 months)
  • Percent of participants that used nicotine replacement therapy and pharmacotherapy(1, 3, and 6 months)
  • Percent of participants that used other behavioral support(1, 3, and 6 months)
  • Percent of participants that used other commercial tobacco products(1, 3, and 6 months)
  • Mean cigarette dependence(1, 3, and 6 months)

Study Sites (1)

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