A prospective comparative study analyzing 3-dimensional changes of a porcine collagen matrix (Mucograft®) versus a free gingival graft for soft tissue grafting to increase the width of keratinized tissue around implants

• Conditions: K08.1; Loss of teeth due to accident, extraction or local periodontal disease

• Registration Number: DRKS00025237
• Lead Sponsor: Zentrum der Zahn-, Mund- und Kieferheilkunde (Carolinum) der Goethe Universität Frankfurt, Zahnärztliches Universitäts-Institut gGmbH, Poliklinik für Zahnärztliche Chirurgie und Implantologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Patients with an age up to 18 years
- Subjects must have voluntarily signed the informed consent form before any study related action
- patient with one or more implants with keratinized mucosa <2mm
-Patient has been informed of the follow-up visits and is willing to return to the clinical center for these follow-up visits (10-14 days, 6 weeks, 3, 6 and 12 months post surgery)

Exclusion Criteria

-Systemic disease that could interfere with dental implant therapy (e.g. uncontrolled diabetes, osteoporosis)
-Bone metabolism disorders and intake of medications (bisphosphonate, steroids)
-Pregnant or breastfeeding women

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess and compare three-dimensional (3D) changes of porcine collagen matrix (Mucograft®) versus autogenous FGG for keratinized mucosa gain around dental implants over a 12-month follow-up period.

Secondary Outcome Measures

Name	Time	Method
- To determine surgical time necessary for both grafting procedures.<br>- To evaluate and compare the clinical appearance of the grafted areas after both grafting procedures.<br>- To establish KT width gain after both grafting procedures.