Study for the Functional Plasticity Mechanism of Opposing Needling at Acupoints of Yangming Meridians in the treatment of hemiplegia after Ischemic Stroke

Not Applicable

• Conditions: hemiplegia after ischemic stroke

• Registration Number: ITMCTR1900002829
• Lead Sponsor: Guangzhou University ofChinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion criteria of hemiplegia after Ischemic Stroke:
1. Within 6 months of onset;
2. Aged 40 to 75 years old;
3. The left cerebral hemisphere and has an infarct with a right limb paralysis, which needs help for daily life;
4. Agree to receive acupuncture;
5. Consciousness, stable vital signs, no obvious mental retardation, no obvious obstacles in hearing, and can be used with basic healers such as rehabilitation training;
6. Volunteer to participate in the study and sign informed consent.
Inclusion criteria of health subject:
1. male or female between 18 and 25 years of age;
2. have no history of health problems;
3. Normal physical examination;
4. have a normal Mini-Mental State Examination (MMSE) (a measure of cognitive impairment);
5. Body mass index (BMI) between 18.5 and 24 kg/m2.

Exclusion Criteria

Exclusion criteria of hemiplegia after Ischemic Stroke:
1. Have been received other treatments which may affect the effect indicator observers of this study and those who do not follow the study protocol;
2. Patients with severe heart, liver, spleen, lung, kidney disease and mental illness;
3. Patients who combined aphasia, deafness, severe cognitive impairment and unable to communicate properly.
4. Not cooperation with acupuncture or basic therapy;
5. Can not complete the treatment, the compliance may not be good;
6. No physical paralysis after illness.
Exclusion criteria of health subject:
1. presence of a cardiac pacemaker or other implanted devices such as brain metal electrodes(except titanium), cochlear implants, or pulse generators;
2. conditions that may potentiate seizures such as a history of epilepsy, sleep deprivation, alcohol dependence, or ingestion of olanzapine or lithium carbonate;
3. pregnancy or lactation.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
volatility of RMT and MEP;Incubation period of RMT and MEP;