NL-OMON38833撤回不适用
Molecular mechanisms behind presumed reduced ovarian reserve and embryo competence in BRCA1/2-mutation carriers in IVF/PGD - Molecular studies on reduced ovarian reserve in BRCA1/2-mutation carriers
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 245 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 245
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational non invasive
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- IVF/PGD treatment for a BRCA1/2 mutation, both female and male mutation carriers
- •- IVF/PGD treatment because of an autosomal dominant genetic disorder transmitted by the male
- •- IVF treatment, including ICSI, for male subfertility
排除标准
- •- Previous diagnosis of female subfertility in controls
- •- Known hereditary disease other than due to BRCA1/2-mutations in the female
- •- Known history of a malignancy in the female
- •- History of cancer treatment in the female
- •- Non-Dutch couples, not able to understand the patient information to give
- •informed consent properly
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