The Role of Central Neck Dissection in Stage N0 Papillary Thyroid Carcinoma

• Conditions: Papillary Thyroid Cancer

• Registration Number: NCT04076514
• Lead Sponsor: Assiut University

Brief Summary

The benefits of prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC). This study main goal is to investigate benefits of prophylactic central neck dissection in clinically node-negative papillary thyroid carcinoma.

Detailed Description

Papillary thyroid carcinoma (PTC) is the most common type of differentiated thyroid carcinoma. Recurrence rate is still high. The standard management is total thyroidectomy. regional lymph node metastasis is noted in recurrent cases. Some studies stated benefits of central neck dissection in orevention of recurrence and others said there is no benefits. so prophylactic central neck dissection (pCND) remain controversial in clinically node-negative (cN0) papillary thyroid carcinoma (PTC).

Study Timeline

• Study First Submitted: 2019-08-28
• Study First Submitted QC: 2019-08-30
• Study First Posted: 2019-09-03
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-10
• Last Update Posted: 2020-07-14
• Study Start: 2020-09-01
• Primary Completion: 2020-09-30
• Study Completion: 2020-11-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• patients with papillary thyroid cancer with clinically node negative.

Exclusion Criteria

• patients with clinical evidence of nodal metastases.
• patients with a previous history of thyroidectomy.
• patients with mixed-type papillary thyroid cancer.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the incidence metastatic lymph node in patients with clinically node-negative thyroid carcinoma who underwent total thyroidectomy with central neck dissection	12 months	numbers of positive histopathological lymph node biopsies postoperative

Trial Locations

Locations (1)

Ahmed Kamel; 🇪🇬 Asyūţ, Asyut, Egypt