CTRI/2020/02/023488
Not yet recruiting
未知
A comparative study of efficacy and safety of Sacubitril/ Valsartan combination with Ramipril on left ventricular ejection fraction in post coronary artery bypass grafting (CABG) patients.
Soumitra Mandal0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: - Health Condition 2: I257- Atherosclerosis of coronary arterybypass graft(s) and coronary artery of transplanted heart with angina pectoris
- Sponsor
- Soumitra Mandal
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •I.Patients planning for CABG
- •II.Age in between 30 to 70 years.
- •III.New York Heart association (NYHA) functional class II\-IV symptoms for heart failure.
- •IV.Ejection fraction of 40% or less.
Exclusion Criteria
- •I.Symptomatic hypotension (Systolic blood pressure \< 100 mm hg).
- •II.Estimated glomerular filtration rate \<30 ml/min/1\.73 m2 \[Gfr estimated by MDRD study equation]
- •III.Hypersensitivity to study medication.
- •IV.Any history of angioedema.
- •V.Concomitant use with any drug formulation containing an angiotensin\-converting enzyme inhibitor.
Outcomes
Primary Outcomes
Not specified
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