NCT04568291Unknown不适用
Clinical Reasearch on Three Dimensional Bionic Capture Network Circulating Tumor Cell in Lung Caner Patients With Bone Metastases
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- SREs（Skeletal related events）
研究概览
简要总结
- Evaluate the feasibility of single cell sequencing technology based on three-dimensional bionic capture network;
- To build a risk prediction model of bone related events based on single cell sequencing;
- To verify the risk prediction model of bone related events by single cell sequencing;
- To verify the comprehensive treatment of non-small cell lung cancer ( NSCLC) bone metastases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-75 years
- •pathology-proven diagnosis of lung cancer and radiographical/pathological evidence of BM
- •no previous treatment for BM
- •good general condition (Eastern Cooperative Oncology Group, ECOG Performance scores: 0-2) with an estimated survival time > 3 months.
排除标准
- 未提供
研究组 & 干预措施
model treatment
Experimental
model treatment
干预措施: model treatment (Other)
routine treatment
Active Comparator
routine treatment
干预措施: routine treatment (Other)
结局指标
主要结局
SREs（Skeletal related events）
时间窗: 1 year
occurance of SREs，including bone pain, pathological fractures, spinal cord compression, hypercalcemia, and the need for surgery or radiotherapy
次要结局
未报告次要终点
研究者
Zhao Hui
Clinical Professor
Shanghai 6th People's Hospital
研究点 (1)
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