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Clinical Trials/NCT06382285
NCT06382285
Not yet recruiting
Not Applicable

The Effect of a Prolonged Peripheral Nerve Block (Utilazing Continuous Adductor Canal Block on the Level of Pain After a Knee Replacement Surgery

Assaf-Harofeh Medical Center0 sites50 target enrollmentOctober 30, 2024

Overview

Phase
Not Applicable
Intervention
Continues peripheral block
Conditions
Knee Replacement Surgery
Sponsor
Assaf-Harofeh Medical Center
Enrollment
50
Primary Endpoint
Pain level
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery

Detailed Description

Knee replacement surgery is one of the common orthopedic surgeries for the treatment of chronic knee pain. The period after knee replacement surgery is accompanied by moderate to severe pain that affects the patient's ability to quickly return to function. Peripheral nerve blockers and analgesia of different types, administered as part of the anesthesia process, are optimal in controlling pain after surgery. After the surgery, the patients are admitted in the orthopedic inpatient department for 2-3 days on average after surgery for follow-up and early physical therapy necessary to achieve good results and return the patient to full function as soon as possible. The level of pain greatly affects the success rate of the patient's rehabilitation. Thus, since the duration of peripheral nerve block activity does not exceed 8-16 hours on average, it is suggested to treat the patients with a prolonged peripheral nerve block (utilizing continuous adductor canal block) for 24 hours after surgery.

Registry
clinicaltrials.gov
Start Date
October 30, 2024
End Date
January 31, 2026
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Zoya Haitov Ben Zikri

Director of the anesthesia department

Assaf-Harofeh Medical Center

Eligibility Criteria

Inclusion Criteria

  • Female and male patients between the ages of 18 and 80 who have signed an informed consent form.
  • ASA is less than 3
  • Spinal anesthesia

Exclusion Criteria

  • Patients with sensitivity to the anesthetic.

Arms & Interventions

Treatment group

ropivacaine (Naropin) 0.2% according to a protocol 8-10 cc per hour up to 24 hours after the surgery

Intervention: Continues peripheral block

Control group

Saline according to a protocol 8-10 cc per hour up to 24 hours after the surgery

Intervention: Continues peripheral block

Outcomes

Primary Outcomes

Pain level

Time Frame: during hospitalization (1-2 days)

Documentation of pain level during the hospitalization days every 12 hours (on a scale of 1-10)

Analgesic use

Time Frame: during hospitalization (1-2 days)

Documentation of pain level during the hospitalization days every 12 hours (on a scale of 1-10). Documentation of analgesic administration in hospitalization.

Secondary Outcomes

  • Physiotherapy(during hospitalization (1-2 days))

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