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临床试验/NCT06382285
NCT06382285尚未招募不适用

The Effect of a Prolonged Peripheral Nerve Block (Utilazing Continuous Adductor Canal Block on the Level of Pain After a Knee Replacement Surgery

Assaf-Harofeh Medical Center0 个研究点目标入组 50 人开始时间: 2024年10月30日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
Pain level

研究概览

简要总结

The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery

详细描述

Knee replacement surgery is one of the common orthopedic surgeries for the treatment of chronic knee pain. The period after knee replacement surgery is accompanied by moderate to severe pain that affects the patient's ability to quickly return to function. Peripheral nerve blockers and analgesia of different types, administered as part of the anesthesia process, are optimal in controlling pain after surgery. After the surgery, the patients are admitted in the orthopedic inpatient department for 2-3 days on average after surgery for follow-up and early physical therapy necessary to achieve good results and return the patient to full function as soon as possible. The level of pain greatly affects the success rate of the patient's rehabilitation. Thus, since the duration of peripheral nerve block activity does not exceed 8-16 hours on average, it is suggested to treat the patients with a prolonged peripheral nerve block (utilizing continuous adductor canal block) for 24 hours after surgery.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Female and male patients between the ages of 18 and 80 who have signed an informed consent form.
  • ASA is less than 3
  • Spinal anesthesia

排除标准

  • Patients with sensitivity to the anesthetic.

研究组 & 干预措施

Treatment group

Experimental

ropivacaine (Naropin) 0.2% according to a protocol 8-10 cc per hour up to 24 hours after the surgery

干预措施: Continues peripheral block (Drug)

Control group

Placebo Comparator

Saline according to a protocol 8-10 cc per hour up to 24 hours after the surgery

干预措施: Continues peripheral block (Drug)

结局指标

主要结局

Pain level

时间窗: during hospitalization (1-2 days)

Documentation of pain level during the hospitalization days every 12 hours (on a scale of 1-10)

Analgesic use

时间窗: during hospitalization (1-2 days)

Documentation of pain level during the hospitalization days every 12 hours (on a scale of 1-10). Documentation of analgesic administration in hospitalization.

次要结局

  • Physiotherapy(during hospitalization (1-2 days))

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Zoya Haitov Ben Zikri

Director of the anesthesia department

Assaf-Harofeh Medical Center

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