Effect of Peripheral Nerve Block on Inflammatory and Nociceptive Biomarkers in a UV-B Burn Model in Humans

Stanford University1 site in 1 country15 target enrollmentOctober 2007

ConditionsPain

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Pain
Sponsor: Stanford University
Enrollment: 15
Locations: 1
Primary Endpoint: Measurement of the effect of a preemptive peripheral nerve block on the hyperalgesic response to an artificially induced sunburn.
Status: Completed
Last Updated: 17 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn. This is important because it may provide information regarding the way that nerve blocks help with the treatment of pain and in particular provide preemptive analgesia.

Registry

clinicaltrials.gov

Start Date

October 2007

End Date

July 2008

Last Updated

17 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Stanford University

Eligibility Criteria

Inclusion Criteria

•Between 18 and 50 years of age
•Fluent in English language
•Provide written informed consent
•Skin pigmentation type II or III\

Exclusion Criteria

•Current use of prescription drugs interfering with study objective
•Use of over-the-counter analgesic/anti-inflammatory drugs within 48h of study participation
•Current acute or chronic pain conditions
•Significant medical conditions including psychiatric, neurological, and dermatological diseases
•Allergies to study drug(s)
•Concomitant participation in other study protocol