Effects of Brachial Plexus Block on Tissue Oxygenation

Completed

• Conditions: Tissue Oxygenation

• Registration Number: NCT05269251
• Lead Sponsor: Gazi University

Brief Summary

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Detailed Description

It has been reported that vasodilation after peripheral nerve blocks increases tissue oxygenation and increases arterial circulation on the ipsilateral side . Near Infrared Spectroscopy (NIRS), a noninvasive measurement method of tissue oxygen level, is used to measure regional hemoglobin oxygen saturation of arterial, venous and capillary blood .

Many studies have compared the effects of upper extremity peripheral nerve blocks on the onset, quality, extent, and postoperative pain of sensory and motor block through axillary, infraclavicular, supraclavicular and interscalene approaches.

The aim of this study is to measure the effects of sympathetic blockade caused by peripheral nerve blocks performed with the axillary, infraclavicular and interscalene approach on tissue oxygenation with Near Infrared Spectroscopy (NIRS), to evaluate and compare the radial artery flow velocity and diameter in the blocked extremity, and to investigate whether there is a relationship with the quality of the sensory and motor block.

Study Timeline

• Study Start: 2021-04-12
• Study First Submitted: 2022-02-25
• Study First Submitted QC: 2022-02-25
• Study First Posted: 2022-03-07
• Primary Completion: 2022-05-31
• Study Completion: 2022-08-01
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-29
• Last Update Posted: 2024-03-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

• ASA I-III patients
• Patients between the ages of 18 and 65
• Patients who applied axillary block
• Patients who applied infraclavicular block
• Patients who applied interscalene block

Exclusion Criteria

• Peripheral nerve disease a history
• History of thrombosis in the extremity to be blocked
• History of embolism in the extremity to be blocked
• Presence of neuropathy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
tissue oxygenation	30 minutes	Measured from both extremities by Near Infrared Spectroscopy for 30 min after brachial nerve block.

Secondary Outcome Measures

Name	Time	Method
Radial artery diameter	30 minutes	measured on the side of the block after brachial nerve block

Trial Locations

Locations (1)

Demet Coskun; 🇹🇷 Ankara, Turkey