comparison of two drugs Fentanyl and Dexmedetomidine for anaesthetising patients undergoing laparoscopic gynaecological surgery
Phase 4
Completed
- Conditions
- Health Condition 1: N938- Other specified abnormal uterine and vaginal bleeding
- Registration Number
- CTRI/2018/09/015593
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1.ASA grade I-II patients
2.Patients undergoing laparoscopic gynaecological surgery
Exclusion Criteria
1.Patient refusal to participate
2.Uncontrolled systemic illnesses
3.Patients with BMI >30
4.Patients with cardiac arrhythmias and conduction blocks
5.Patients on beta blockers
6.Patients with documented autonomic dysfunction
•Known hypersensitivity to Opioids or Dexmeditomidine
•Patients on any drug included in the study for chronic treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of recovery profile in both groupsTimepoint: during the period of surgery and till 6 hours postoperatively
- Secondary Outcome Measures
Name Time Method 1.Intra-operative Hemodynamic profile <br/ ><br>2. serum cortisol levels to assess stress response <br/ ><br>3.PONV <br/ ><br>4.Patient satisfaction score <br/ ><br>5.Time to first rescue analgesic <br/ ><br>Timepoint: 1.Intraoperative hemodynamic parameters every 30 min for the duration of surgery <br/ ><br>2.serum cortisol levels just before induction, at 30 min and at 60 min <br/ ><br>3. patient will be followed up for a period of 6hrs postoperatively