临床试验/NCT02299882

NCT02299882Unknown不适用

Surgical Infection Rates With Adjunct Vancomycin Compared to Standard Peri-Operative IV Antibiotics

Spectrum Health Hospitals1 个研究点分布在 1 个国家目标入组 700 人开始时间: 2012年8月最近更新: 2014年11月24日

适应症

干预措施

试验速览

阶段: 不适用
发起方: Spectrum Health Hospitals
入组人数: 700
试验地点: 1
主要终点: Surgical wound infection rate, both deep and superficial infections

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Determine the effect of Vancomycin Powder added to the surgical wound at closure on surgical infection rates.

详细描述

Study will be blinded and randomized 1:1 to either Vancomycin Powder at closure or no vancomycin powder at closure.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Single Group
主要目的: Prevention
盲法: Single (Participant)

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•All adult, 18 years or greater undergoing posterior approach spinal surgery

排除标准

•Prisoner, pregnant women, patient under the age of 18, those of diminished decision making capacity.
•patients with known reaction to Vancomycin.
•patients having surgery specifically for spine infection
•patients having ADCF or ALIF

研究组 & 干预措施

Vancomycin

Experimental

Patient will receive Vancomycin powder to the incision just before skin closure

干预措施: Vancomycin (Drug)

结局指标

主要结局

Surgical wound infection rate, both deep and superficial infections

时间窗: 12 weeks post surgery

次要结局

Post-operative rate of MRSA infections.(12 weeks post surgery)

研究者

发起方

Spectrum Health Hospitals

申办方类型

Other

责任方

Principal Investigator

主要研究者

Jason A Squires, DO

Physician

Spectrum Health Hospitals

研究点 (1)

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