Effect of Platelet Rich Plasma ( PRP ) Applied During Knee Arthroscopy on Pain, Function and Quality of Life - A RCT With a Follow up of 12 Months

Ruhr University of Bochum1 site in 1 country58 target enrollmentJuly 2010

ConditionsKnee Osteoarthritis Cartilage Damage Meniscal Tear

Overview

Phase: Phase 4
Intervention: Not specified
Conditions: Knee Osteoarthritis
Sponsor: Ruhr University of Bochum
Enrollment: 58
Locations: 1
Primary Endpoint: pain ( VAS )
Status: Completed
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to investigate reduction of pain, gain of function and improvement of life quality by intraoperative applied platelet- rich- plasma ( PRP ) during knee arthroscopy for degeneration and osteoarthritis OA by conducting a randomized- controlled, double-blinded trial ( RCT ) including 58 patients with a follow up of 12 months and pain, assessed by Visual- Analogue Scale (VAS) after 6 months as primary endpoint.

Registry

clinicaltrials.gov

Start Date

July 2010

End Date

December 2012

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Ruhr University of Bochum

Responsible Party

Principal Investigator

Christian Duif MD

PostDoc Department of Orthopaedics

Ruhr University of Bochum

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

pain ( VAS )

Time Frame: 6 months

measurement of pain using a 100 mm VAS as platelet- rich-plasma demonstrated temporarily analgetic effects up to 6-9 months after application.

Secondary Outcomes

quality of life ( physical und mental summaries of SF-36 German version )(6 weeks, 6 months and 12 months)
knee function (Lysholm-score )(6 weeks, 6 months, 12 months)
pain ( VAS )(6 weeks, 12 months)