Can a simple monitoring method predict worsening of brain injury towards Brain death
Not Applicable
- Conditions
- Health Condition 1: S062- Diffuse traumatic brain injuryHealth Condition 2: I609- Nontraumatic subarachnoid hemorrhage, unspecified
- Registration Number
- CTRI/2020/04/024702
- Lead Sponsor
- Department of Neuroanaesthesia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients between the age of 15 and 70 admitted to the neurosurgery or neurology ICU with severe brain damage of known etiology- Subarachnoid hemorrhage (SAH), Traumatic brain injury (TBI), Intracerebral hemorrhage (ICH), Ischaemic stroke, comatose (GCS- 3 and FOUR score- zero)
Exclusion Criteria
1.Refusal of consent by relative
2.CNS infections as the cause of coma/ Severe sepsis
3.Severe facial trauma including forehead scalp hematomas
4.Unevacuated SDH
5.Polytrauma â?? Lung injury and prior history of respiratory disease impeding ventilation and oxygenation
6.Prior history of cardiovascular disease
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To observe the changes in regional cerebral oxygen saturation (rSO2) in patients following severe brain damage <br/ ><br>Timepoint: Hourly assessment <br/ ><br>
- Secondary Outcome Measures
Name Time Method To assess the role of NIRS as a non-invasive ancillary method for the diagnosis of brain deathTimepoint: hourly assessment till brain death confirmed clinically