Caffeine Intake and Additive Effects on Cognition

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Caffeine Intake; Other: Placebo Intake

• Registration Number: NCT02647567
• Lead Sponsor: Universidade Federal do Rio de Janeiro

Brief Summary

Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory. So, understanding that a positive effect of aerobic exercise can be displayed also on cognition, as caffeine, when in proper proportions, the investigators do not know if the joining of the two strategies into a single activity would be able to promote additional effects enhancing cognitive processes related to memory, attention, and motor reaction time.

Detailed Description

Determine if 500 mg of caffeine can generate additional effects to 30 minutes of aerobic exercise enhancing cognitive memory tasks (Rey Auditory Verbal Learning Test - RAVLT), attention (sustained attention span; working speed; Percentual of errors by confusion) and simple reaction time (SRT).

Study Timeline

• Study Start: 2015-05
• Primary Completion: 2015-11
• Study Completion: 2015-12
• Study First Submitted: 2015-12-05
• Status Verified: 2016-01
• Study First Submitted QC: 2016-01-04
• Last Update Submitted: 2016-01-04
• Study First Posted: 2016-01-06
• Last Update Posted: 2016-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

• Fighting men
• Low levels of consumption of caffeine daily

Exclusion Criteria

• Use more than 400 mg caffeine day
• Mental diseases
• Cognitive deficits

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Caffeine Intake	Caffeine Intake	The experimental group ingest 500 mg of caffeine before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.
Placebo Intake	Placebo Intake	The control group ingest 500 mg of placebo before (60 min) aerobic exercise (procedure double blind), and perform a battery of neuropsychological and psychomotor tests. 1 min and 30 min after the exercise the subjects perform a new battery of neuropsychological and psychomotor tests.

Primary Outcome Measures

Name	Time	Method
Simple Reaction Time	Acute Change from Baseline Psychomotor test to 1 min after aerobic exercise, and after 30 min
Rey Auditory Verbal Learning Test	Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min
Sustained Attention Test	Acute Change from Baseline Cognitive test to 1 min after aerobic exercise, and after 30 min