Correlation between scar biomechanical properties and skin microbiome in burn patients
- Conditions
- Diseases of the skin and subcutaneous tissue
- Registration Number
- KCT0005228
- Lead Sponsor
- Hallym University Medical Center-Hangang
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 152
1.subjects according to the burn degree (n=28 in each group; three groups: second-degree superficial partial-thickness burns, second-degree deep partial-thickness burns, and third-degree burns).
2. patients with completely healed burn wounds and burn patients with hypertrophic scars after 3 months (n=39).
3. patients with a burn injury who complain of pruritus and score 5 points or more on the numerical rating scale even with medication and physical therapy for more than 1 month (n=29).
-If steroids or antibiotics are applied or taken within 2 weeks
-Women who are pregnant or lactating and those who may be pregnant
-If you have a chronic disease that can affect the skin environment, such as diabetes and skin disease
-In case of infection of scar area
-Electric burn
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method skin microbiome
- Secondary Outcome Measures
Name Time Method scar elasticity, trans-epidermal water loss, erythema, melanin, scar thickness;VSS; Vancouver scar scale, POSAS; Patient and observer scar assessment scale;ESR, CRP, IL-6, lipopolysaccharide