A clinical trial to study the efficacy of low level laser therapy in older individuals after single visit endodontic treatment.

Not yet recruiting

• Conditions: Chronic apical periodontitis,

• Registration Number: CTRI/2023/01/048830
• Lead Sponsor: Nandhita Murugavel

Brief Summary

This study is a randomized, single-blinded, single-center trial evaluating the efficacy of Low Level Laser Therapy in the management of postoperative pain after Single Visit Endodontic Treatment in symptomatic apical periodontitis cases in an older age group. The primary outcome measures of this study are to record and evaluate the pain Visual Analogue Scale scores  preoperatively and postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy or sham laser, which will be the mock application of the laser.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-12-27
• Study Start: 2023-01-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• Patients between the age group of 40-65 years.
• Permanent mandibular premolars and molars having symptomatic irreversible pulpitis with symptomatic apical periodontitis 3.
• Pre-operative pain VAS score: greater than 4.
• Tenderness on percussion with percussion VAS score: greater than 4 5.
• Early or lingering response to cold and EPT pulp sensibility testing 6.

Exclusion Criteria

• Systemic disorders: Cardiovascular system (CVS) disorders, respiratory disorders, asthma patients, coagulation disorders, thyroid disorders, psychiatric disorders, immunocompromised patients.
• Medical drug intake: patients who have taken analgesics, corticosteroids, sedatives, muscular relaxants, anti-clotting agents or antibiotics 12 hours prior to the intervention.
• Pregnant individuals.
• Radiographically detected large periapical lesions or abscesses, space infections 5.
• History of previous root canal treatment in the same tooth 6.
• Periodontally compromised tooth (>grade I mobility, pocket depth >4 mm).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and	To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and | postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic | Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older | individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy | or sham laser application.
individuals treated with single visit endodontics followed by interventional application of low level laser therapy	To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and | postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic | Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older | individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy | or sham laser application.
postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic	To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and | postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic | Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older | individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy | or sham laser application.
or sham laser application.	To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and | postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic | Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older | individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy | or sham laser application.
Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older	To evaluate the pain Visual Analogue Scale (VAS) scores preoperatively and | postoperatively on the 1st, 2nd, 3rd, 5th, 7th and 30th day in Symptomatic | Irreversible Pulpitis with Symptomatic Apical Periodontitis cases in older | individuals treated with single visit endodontic treatment followed by interventional application of low level laser therapy | or sham laser application.

Secondary Outcome Measures

Name	Time	Method
Pre-operative or baseline percussion VAS scores will also be compared with 7th	day percussion VAS score.

Trial Locations

Locations (1)

KLE Societys Institute of Dental Sciences, Bangalore; 🇮🇳 Bangalore, KARNATAKA, India

KLE Societys Institute of Dental Sciences, Bangalore

🇮🇳Bangalore, KARNATAKA, India

Nandhita Murugavel

Principal investigator

8073054240

nandhita.murugavel@yahoo.co.in