Effects of Betaine Supplementation Combined or Not With Creatine Supplementation on Muscle Creatine Content and Strength
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- strength
研究概览
简要总结
It has been suggested that betaine supplementation may improve muscle strength by increasing muscle creatine content. However, there is no data supporting this assumption. The investigators speculate that betaine supplementation could enhance intramuscular creatine content, which would result in strength improvements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •physically inactive
- •non-obese
排除标准
- •skeletal muscle disturbance
- •cardiovascular disturbance
- •use of dietary supplements
研究组 & 干预措施
creatine plus betaine
will receive creatine (20g/d) plus betaine (2g/d) throughout 10 days
干预措施: creatine plus betaine (Dietary Supplement)
placebo (dextrose)
will receive dextrose(20g/d)throughout 10 days.
干预措施: dextrose (Dietary Supplement)
betaine
will receive betaine (2g/d) throughout 10 days
干预措施: betaine (Dietary Supplement)
creatine
will receive creatine monohydrate (20g/d) throughout 10 days
干预措施: creatine (Dietary Supplement)
结局指标
主要结局
strength
时间窗: after 10 days
次要结局
- intramuscular creatine content(after 10 days)
研究者
Bruno Gualano
Principal Investigator
University of Sao Paulo