Exercise Training in Chronic Kidney Disease
- Conditions
- Chronic kidney diseaseUrological and Genital Diseases
- Registration Number
- ISRCTN36489137
- Lead Sponsor
- niversity Hospitals of Leicester (UK)
- Brief Summary
1. 2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/29412705 (added 08/05/2019) 2. 2018 secondary analysis in: https://www.ncbi.nlm.nih.gov/pubmed/30746138 (added 08/05/2019) 3. 2019 secondary analysis in: https://www.ncbi.nlm.nih.gov/pubmed/31054219 (added 08/05/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 41
1. Male and female aged between 18 and 100 years
2. Established Chronic kidney disease (Stages 3b-5)
3. Attending Nephrology outpatient clinics in the Leicester region
1. Age <18 years
2. Unfit for the exercise programme due to physical impairment and significant co-morbidity (unstable hypertension, potentially lethal arrhythmia, myocardial infarction within previous 6 months, unstable angina, active liver disease, uncontrolled diabetes mellitus (HbA1c >9%), advanced cerebral or peripheral vascular disease)
3. Insufficient command of English to give informed consent or comply with the testing and training protocol. If the results indicate that the intervention is useful, future larger studies will include provision for those whose first language is not English.
4. BMI> 40 with waist circumference >102cm for males and >88 for females. Two measures of obesity have been included here to allow for the inclusion of individuals with a high BMI due to a larger muscle mass, as BMI is unable to discriminate between fat mass and fat free mass.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Muscle strength (total weight lifted during training sessions and estimated 1 repetition maximum of quadriceps extension) measured at 6 weeks, 12 weeks, 18 weeks
- Secondary Outcome Measures
Name Time Method