To determine the efficacy of epidural labor analgesia in prevention of postpartum depression a case controlled study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- To determine the efficacy of epidural labor analgesia in prevention of postpartum depression using Edinburgh Postnatal Depression Scale [EDPS]
研究概览
简要总结
After Institutional Ethics Committee approval and Informed Patient Consent, a total 72, patients of ASA I-III, and age group of 18 to 30 years planning to give birth electively via a normal vaginal route, allocated into two groups (36 in each group),
In this study
Group I Epidural Labor Analgesia
Group II No intervention
Patient preference for the decision of the group slection will be done
In group 1
18 G Epidural catheter placement after local infiltration at level L3-L4,L4-L5 when cervical dilatation will reach 3-5cm
Test dose of 3ml Lidocaine 1.5 %with adr [1:200000] will be given
Patient will receive a bolus dose of ropivacaine 0.2% [ 10 -20ml] plus fentanyl 10mcg via epidural catheter
Followed by continuous infusion of 0.2% ropivacaine 20ml Plus 40mcg fentanyl at rate of 6 to 10ml per hr
Then following parameters to be study
1 maternal Hemodynamics
2fetal heart rate
3 pain [ vas score]
4Apgar score
5 edinburgh postnatal depression scale
6 maternal satisfaction scale
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- Female
入选标准
- •Patient of age group of 18-30 years, planning to give birth electively via normal vaginal route American Society of Anesthesiologists (ASA)physical status I-III Singleton pregnancy.
排除标准
- •Patient refusal Infection at intervention site Coagulation disorder Intracranial pathology Allergy to study drugs Active neurological/Psychiatry disease Complicated obsteteic conditions [ twin,GDM,SPE].
结局指标
主要结局
To determine the efficacy of epidural labor analgesia in prevention of postpartum depression using Edinburgh Postnatal Depression Scale [EDPS]
时间窗: At 2weeks 4weeks 6weeks from date of delivery
次要结局
- To study the effect of epidural analgesia on duration of labour(To study the effect of epidural analgesia on fetal outcome using APGAR score)
研究者
Nitesh kumar
Kgmu Lucknow up