Skip to main content
Clinical Trials/NCT06150404
NCT06150404
Terminated
Not Applicable

Parents' Voice and White Noises in Neonatal Intensive Care Unit: Efficacy Evaluation Against Noises' Damage - a Randomized Controlled Trial

Istituto Giannina Gaslini1 site in 1 country11 target enrollmentFebruary 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Premature Infant Disease
Sponsor
Istituto Giannina Gaslini
Enrollment
11
Locations
1
Primary Endpoint
Reduction of heart rate alteration
Status
Terminated
Last Updated
last year

Overview

Brief Summary

The goal of this Randomized Controlled Trial is to test the efficacy of listening to white noises and parental voices against environmental noise damage in premature babies admitted to the Newborn Intensive Care Unit.

The main question it aims to answer is:

• Could the combined use of white noises and maternal and/or paternal voices reduce the negative outcomes of continuous exposure to hospital noises on newborns hospitalized in a Neonatal Intensive Care Unit?

Participants in the intervention group will listen to a recorded track composed of white noises and voices of their parents who read a story or sing a lullaby from the day of enrollment until the day of discharge, for 4 hours per day.

Researchers will compare the intervention group with the control group (who will receive the usual care provided without any intervention on the noise level) to see if babies enrolled in the intervention group show fewer events of tachycardia, tachypnea, desaturation, apnoea, and language or hearing impairment.

Registry
clinicaltrials.gov
Start Date
February 1, 2024
End Date
December 31, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Silvia Rossi

Doctor in Methodology Research in Nursing

Istituto Giannina Gaslini

Eligibility Criteria

Inclusion Criteria

  • Patients admitted to the NICU with gestational age at birth ≥ 31 weeks (as this is the age at which sound perception is ≥ 40 dB and there is predictable clinical stability to allow intervention delivery without excessive interruptions)
  • Patients admitted to the NICU who reach gestational age ≥ 31 weeks
  • Patients monitored with the following types of monitors: Masimo rainbow SET™ (Masimo); Infinity® Delta (Draeger); Infinity® Acute Care System (Draeger); Efficia CM (Philips).

Exclusion Criteria

  • Patients with gestational age at birth \< 31 weeks
  • Patients affected by meningitis or severe cerebral insults, congenital brain anomalies, congenital syndromes with suspected or known brain dysfunction
  • Patients diagnosed with hypoxic-ischemic encephalopathy
  • Patients with significant airway abnormalities resulting in altered breathing during sleep
  • Patients with terminal illnesses
  • Patients with congenital anomalies of the face, ears, skull, or brain
  • Patients with non-bacterial congenital infections
  • Patients with congenital hearing deficits
  • Patients whose parents or legal guardians refuse to participate in the study
  • Patients already enrolled in other clinical studies.

Outcomes

Primary Outcomes

Reduction of heart rate alteration

Time Frame: Through study completion, an average of 2 year

Reduction, in the patients enrolled in the intervention group compared to the control group, in episodes of heart rate alteration associated with noises \> 45 dB (nursing diagnosis: risk of tachycardia - HR \>180 bpm - correlated with environmental exposure to noises \> 45dB).

Reduction of oxygen saturation alteration

Time Frame: Through study completion, an average of 2 year

Reduction, in the patients enrolled in the intervention group compared to the control group, in episodes of oxygen saturation alteration associated with noises \> 45 dB (nursing diagnosis: risk of desaturation - SpO2 \<90% - correlated with environmental exposure to noises \> 45dB).

Reduction of respiratory rate alteration

Time Frame: Through study completion, an average of 2 year

Reduction, in the patients enrolled in the intervention group compared to the control group, in episodes of respiratory rate alteration associated with noises \> 45 dB (nursing diagnosis: risk of tachypnoea - RR \>60 breaths per minute - correlated with environmental exposure to noises \> 45dB).

Reduction of episodes of apnoea

Time Frame: Through study completion, an average of 2 year

Reduction, in the patients enrolled in the intervention group compared to the control group, in episodes of apnoea associated with noises \> 45 dB (nursing diagnosis: risk of apnoea - HR \<100 bpm and SpO2 \<90% - correlated with environmental exposure to noises \> 45dB).

Secondary Outcomes

  • Reduction in Language Development Alterations(From enrollment unitl 3 years of age)
  • Reduction in Hearing Development Alterations(From enrollment unitl 3 months of age)

Study Sites (1)

Loading locations...

Similar Trials