NL-OMON40784
Completed
Not Applicable
THE EFFECT OF THORACIC EPIDURAL ANAESTHESIA WITH GENERAL ANAESTHESIA ON MEAN SYSTEMIC FILLING PRESSURE, VENOUS RETURN AND CARDIAC FUNCTION - Effect of TEA with GA on Pmsf, VR and cardiac function
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- effecten van sympathicusblokkade door epidurale anesthesie met algehele anesthesie
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 5
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All adult patients scheduled for lung surgery under thoracic epidural and general anaesthesia
Exclusion Criteria
- •\* Participation in a trial on investigational drugs within 3 months prior to the study
- •\* Hemodynamic instability prior to start of measurements with the systolic blood pressure decreasing more than 30% below the pre\-anaesthetic value or a mean arterial pressure (MAP) \< 60 mm Hg, central venous pressure (CVP) \>18 mm Hg and/ or a cardiac index \< 2\.0 L\*min\-1 or dependence on high dosages of inotropic drugs after induction of general anaesthesia and before TEA.
- •\* Severe arrhythmias
- •\* Intra\-cardiac shunts
- •\* Prior diagnosis of aberrant cardiovascular anatomy
- •\* Symptomatic peripheral vascular disease
- •\* Severe chronic obstructive pulmonary disease (GOLD III or IV, or proven existence of lung bullae)
- •\* Clinically significant aortic aneurysm
- •\* Significant valvular regurgitation
- •\* Use of lithium medication
Outcomes
Primary Outcomes
Not specified
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