Being Touched in Persistent Pain: Mapping the Association Between Pleasant Touch and Central Sensitization in Patients With Persistent Pain.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Perception of pleasant touch
研究概览
简要总结
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives. The study also aims to examine how these experiences relate to pain sensitivity and body awareness. The main questions it aims to answer are:
How is the perception of pleasant touch associated with central sensitization and interoceptive awareness in individuals with chronic pain?
Does the perception of pleasant touch differ between individuals with different dominant pain mechanisms (nociceptive, neuropathic, and nociplastic)?
Participants referred to a specialist Pain Clinic in Västra Götaland as part of their regular care will be invited to take part. Those who consent will complete online questionnaires assessing pain, experience and exposure to touch, interoceptive awareness, and central sensitization. Clinical data such as pain diagnosis and medical history will also be collected.
详细描述
This observational study aims to investigate how individuals with chronic pain experience pleasant touch and how these experiences relate to central sensitization, interoceptive awareness, and different pain mechanisms.
Participants referred to the Pain Clinic in Västra Götaland as part of their regular care will be invited to participate. After receiving written and oral information and providing informed consent, participants will complete digital questionnaires via a secure electronic data capture system (REDCap).
The questionnaires assess experience and exposure to pleasant social touch, central sensitization (Central Sensitization Inventory, CSI), interoceptive awareness (Multidimensional Assessment of Interoceptive Awareness, MAIA-2), and pain intensity (Numeric Pain Rating Scale, NPRS). A newly developed questionnaire will be used to assess perception and exposure to social touch, including qualitative components.
Clinical data will be collected during routine physician visits and include pain diagnosis, pain distribution, symptom severity, comorbidities, and medication use. Questionnaire data and clinical data will be linked using participant ID numbers. Treating physicians will not have access to questionnaire responses to reduce the risk of bias.
Additional data may be obtained from the Swedish National Registry for Pain Rehabilitation (NRS), where applicable.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years and older
- •Referred to and accepted for assessment at Pain Clinic (Smärtteam) Västra Götaland due to persistent pain (duration ≥ 3 months)
- •Able to read and complete self-report questionnaires in Swedish
排除标准
- •Inability to read or complete self-report questionnaires in Swedish
- •Need for interpreter support
研究组 & 干预措施
Chronic Pain Patients
Individuals with chronic pain referred to a specialist pain clinic in Västra Götaland. Participants will complete questionnaires assessing pain, experience and exposure to pleasant touch, interoceptive awareness, and central sensitization. Clinical data will be collected as part of routine care.
结局指标
主要结局
Perception of pleasant touch
时间窗: At baseline
Perception of pleasant touch assessed using a study-specific questionnaire measuring experience and exposure to social touch.
次要结局
- Central sensitization(At baseline)
- Interoceptive awareness(At baseline)