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Clinical Trials/NCT01510392
NCT01510392
Completed
Not Applicable

Prospective Evaluation of Optical Coherence Tomography Usage in the Screening of Eye Diseases

Oregon Health and Science University1 site in 1 country118 target enrollmentJanuary 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Glaucoma
Sponsor
Oregon Health and Science University
Enrollment
118
Locations
1
Primary Endpoint
OCT screening efficacy for detection of early stage eye diseases in comparison to the current standard of care methods
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The primary goal of the trial is to show that optical coherence tomography (OCT) technology can be used to effectively screen for diseases of the eye including glaucoma, macular diseases and keratoconus. Glaucoma is a disease that causes permanent vision loss and is usually accompanied by increased eye pressure. Macular diseases affect sharp, central vision. Keratoconus is a disease that affects the cornea (clear surface covering the colored part of the eye).

Detailed Description

The identification of many eye diseases would significantly benefit from earlier detection than is available with typical eye exams. Optical coherence tomography (OCT) is an imaging technology that can perform non-contact cross-sectional imaging of tissue structure in real time. It is similar to ultrasound B-mode imaging, except that OCT measures the intensity of reflected light rather than sound waves.

Registry
clinicaltrials.gov
Start Date
January 2012
End Date
February 2, 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

David Huang

Michael Chiang, MD, Professor, Provisional, Department of Ophthalmology and Medical Informatics & Clinical Epidemiology

Oregon Health and Science University

Eligibility Criteria

Inclusion Criteria

  • Participant undergoing a screening examination at the Casey Eye Institute Outreach Van.
  • Participants must be between the ages of 18 and 89 years old.

Exclusion Criteria

  • Inability to give informed consent.
  • Inability to maintain stable fixation for OCT imaging

Outcomes

Primary Outcomes

OCT screening efficacy for detection of early stage eye diseases in comparison to the current standard of care methods

Time Frame: 1 year

The primary goal of the trial is to show that OCT technology, specifically the FDA cleared iVue, can be used to effectively screen for glaucoma, macular diseases and keratoconus. The rate of detection of these diseases detected using OCT will be compared to the rate of detection by the physician's exam.

Study Sites (1)

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