NCT03761381招募中不适用
Using Optical Coherence Tomography and Noninvasive Retinal Amyloid Imaging to Capture Retinal Changes Associated With Dementia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Retinal amyloid protein detection
研究概览
简要总结
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to:
- Detect retinal blood vessel and blood flow changes in participants with dementia.
- Detect amyloid protein deposits in the retinas of participants with dementia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Retinal amyloid protein detection
时间窗: 1 day
OCT and OCT angiography will be used to detect levels of amyloid proteins deposits within the retina layers on the single enrollment visit only. An increase in the protein detection is expected in the dementia group.
次要结局
- Decreased blood flow(1 day)
- Decreased retinal perfusion(1 day)
研究者
David Huang
David Huang, MD, PhD, Peterson Professor of Ophthalmology and Professor orf Biomedical Engineering
Oregon Health and Science University
研究点 (1)
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