Bizarreness and Anomalous Self Experiences in Schizophrenia: Pilot Study on Diagnostic Decision-Making
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 12
- 试验地点
- 1
- 主要终点
- Correlation between Praecox Feeling and Self Disorders
研究概览
简要总结
Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia.
However, determining factors of this phenomena, whether cognitive or subjective, remains poorly studied.
Furthermore, Self-Disorders are alterations of the first-person experience regarded as specific of the disease. The investigators plan to study in an exploratory way the phenomenological and subjective links between Praecox Feeling and Self Disorders determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.
详细描述
Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia. However, subjective, cognitive or neurophysiologic aspects of this phenomena remains poorly studied.
Furthermore, Self-Disorders (SD) are alterations of the first-person experience and of sense of agency, regarded as specific of Schizophrenia. Unlike Praecox Feeling, clinical, cognitive and neuropsychological determinants of SD are increasingly studied.
The investigators plan to study in an exploratory way the links between Praecox Feeling and SDs determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.
As a secondary outcome, the investigators will control this correlation by a comparison between SDs evaluation and clinician subjectivity.
The present study also plan to evaluate the associations between Praecox Feeling and clinical features, low and high cognitive level with attentional and social cognition evaluations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •People with a diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria.
- •Psychiatric medical situation judged clinically stable : no change of main antipsychotic in treatment in last 15 days.
- •People who has given his non-opposition
- •Patients affiliated to a social security system
排除标准
- •Previous meeting of the participant with one of the investigators involved in the clinical assessment and scoring of the study scales.
- •Person with a moderate to severe intellectual disability (clinical criteria).
- •Person with a neurological pathology with cognitive impact
- •Patients with legal protection
结局指标
主要结局
Correlation between Praecox Feeling and Self Disorders
时间窗: 2 months
Comparison between Examination of Anomalous Subjective Experience (EASE) total score evaluated at third visit and mean of Praecox Feeling intensity measured by a visual analog scale (VAS) evaluated at each visit. Examination of Anomalous Subjective Experience is a 5-item interview asked by the investigator. Visual Analog Scale (VAS) is a scale that evaluates the level of strangeness felt during the patient/investigator encounter. It goes from 0 (no strangeness feeling) to 100 (maximal strangeness feeling).
次要结局
- Correlation between Praecox Feeling and symptomatic dimensions(2 months)
- Correlation between the patient's judgment and the quality of the meeting(2 months)
- Correlation between Praecox Feeling intensity and Self Disorders intensity(2 months)