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Clinical Trials/NCT03023670
NCT03023670
Completed
Not Applicable

Ventilatory Patterns During Cardiopulmonary Bypass In Pediatric Cardiac Surgery

Assiut University1 site in 1 country68 target enrollmentJanuary 2017
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ConditionsLung Injury, Acute

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Lung Injury, Acute
Sponsor
Assiut University
Enrollment
68
Locations
1
Primary Endpoint
Change from Baseline Computerized tomography chest (CT chest) within 7 days postoperative
Status
Completed
Last Updated
7 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The lung is at risk for ischemic insults during total cardiopulmonary bypass because lung perfusion is maintained solely by the bronchial arterial system

Detailed Description

The study will be performed in the pediatric cardiothoracic unit, pediatric Assiut University Hospital. After obtaining approval from the local ethics committee and written informed parents consent 60 patients will be included in this study according to the following criteria:

Registry
clinicaltrials.gov
Start Date
January 2017
End Date
April 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sayed Kaoud Abd-Elshafy

Associate profossor of anesthesiology and critical care

Assiut University

Eligibility Criteria

Inclusion Criteria

  • •Elective cardiac surgery
  • •Ventricular septal defect (VSD).
  • •Atrial septal defect (ASD)

Exclusion Criteria

  • •Cyanotic heart disease.
  • •Patients with preoperative chest problems.
  • •Patients with known renal or hepatic dysfunctions.
  • •Planned off-pump cardiac surgery.
  • •Emergency cardiac surgery.

Outcomes

Primary Outcomes

Change from Baseline Computerized tomography chest (CT chest) within 7 days postoperative

Time Frame: preoperative and within the first 7 days postoperative

Secondary Outcomes

  • Arterial blood gases(Within the first 7 days postoperative)
  • Mechanical ventilation(Within the first 7 days postoperative)
  • Intensive care unit stay(Within the first 7 days postoperative)
  • Intubation time(Within the first 7 days postoperative)

Study Sites (1)

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