Effect of sildenafil on treatment of oligohydramnios
Not Applicable
Recruiting
- Conditions
- Oligohydramnios.Oligohydramnios
- Registration Number
- IRCT20170917036227N3
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 52
Inclusion Criteria
singleton pregnancy
Gestational age 28 weeks and above
Ultrasonically diagnosed oligohydramnios in the third trimester ( defined as Amniotic Fluid Index (AFI) blow 8 cm )
Exclusion Criteria
Intrauterine growth restriction (IUGR)
Fetal Anomaly
Abnormal Blood Flow Patterns by Color Doppler flow imaging
Abnormal NST
Treatment with Prostaglandin synthetase inhibitors
Rupture of membranes
Active Labor
Chronic Hypertension
Overt Diabetes Mellitus
Maternal Hydration therapy contraindications ( like renal, respiratory or cardiac diseases )
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amniotic fluid index. Timepoint: 24 hours after starting treatment and every week after discharge for up to 6 weeks. Method of measurement: Ultrasonography.
- Secondary Outcome Measures
Name Time Method Duration of intervention until delivery. Timepoint: During intervention. Method of measurement: check list.;Infant weight. Timepoint: At the end of the study. Method of measurement: Balance (in kilograms and grams).;NICU Admission. Timepoint: At the end of the study. Method of measurement: File information.;APGAR Score. Timepoint: At the end of the study. Method of measurement: File information.;Type of delivery. Timepoint: At the end of the study. Method of measurement: File information.;Gestational Age at birth. Timepoint: At the end of the study. Method of measurement: File information.