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临床试验/IRCT2014072818625N1
IRCT2014072818625N1已完成2 期

Comparison of sildenafil effects and placebo on mortality and morbidity in patients with severe mitral stenosis and reactive pulmonary hypertension after mitral valve replacement

Tehran Heart Center0 个研究点目标入组 62 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
62

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
no limit 至 no limit(—)
性别
All

入选标准

  • Patients with severe mitral stenosis; Pulmonary artery pressure more than 35 mm Hg in trans esophageal echocardiography; Reactive pulmonary hypertension according right heart catheterization (difference between mean pulmonary artery pressure and Pulmonary Capillary Wedge Pressure> 12mmhg)
  • Exclusion criteria: Necessity of nitrate; Significant hypotension after first dose of sildensfil; Mitral regurgitation more severe than moderate degree; Necessity of aortic or tricuspid valve replacement; Concomitant Coronary artery bypasses graft surgery

排除标准

  • 未提供

研究者

发起方
Tehran Heart Center

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