Evaluate the effectiveness of Acute Flu Vaccination on Recurrent Cardiovascular Events (AFLUENT): A Pilot Randomised Clinical Trial
Not Applicable
Recruiting
- Conditions
- Acute myocardial infarction (Type 1)Cardiovascular - Coronary heart disease
- Registration Number
- ACTRN12623001296628
- Lead Sponsor
- Royal Perth Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Acute type 1 myocardial infarction
Exclusion Criteria
a) Influenza vaccination in the previous 3 months
b) Previous anaphylactic reaction to influenza vaccination
c) Previous anaphylactic reaction to any component of influenza vaccine (if no suitable alternate vaccine is available)
d) Intercurrent active infection or febrile illness
e) Prior history of Guillain-Barré Syndrome within 6 weeks of previous influenza vaccination
f) Other severe medical condition with life expectancy <1 year
g) Unable or unwilling to provide informed consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite primary outcome, including incidence of cardiovascular death, myocardial infarction and stroke.[Data linkage: Patient medical records, and Data Linkage Services, Department of Health, Government of Western Australia 12 months after randomisation.]
- Secondary Outcome Measures
Name Time Method