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Clinical Trials/NCT03330262
NCT03330262
Completed
N/A

Head-Mounted Vibrotactile Prosthesis for Patients With Chronic Postural Instability

Barron Associates, Inc.1 site in 1 country13 target enrollmentOctober 1, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Vestibular Disorder
Sponsor
Barron Associates, Inc.
Enrollment
13
Locations
1
Primary Endpoint
Difference in Dynamic Gait Index (DGI)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The goal of this study is to evaluate a tactile prosthesis that provide individuals who have demonstrated chronic imbalance with help to maintain a correct sense of orientation with respect to the gravity and improve posture control.

Detailed Description

The goal of this study is to evaluate a tactile prosthesis that provide individuals who have demonstrated chronic imbalance with help to maintain a correct sense of orientation with respect to the gravity and improve posture control. Chronic imbalance leads to significant problems. This study is designed to evaluate a device which can potentially improve the balance of these patients. The participant will be asked to come to Washington University on three occasions for approximately 2 hours. Between visits, they will be asked to use the device daily (intervention condition) or to not use the device (control condition) for a prescribed period of time doing different activities. They will be provided written instructions from a physical therapist that will be determined by their individual ability. The activities will be typical exercises that are given to people with balance disorders. After 6 weeks of home use, participants will return for the second visit, and will repeat the evaluation. They will then return home and complete the either the control or intervention condition (which was not done the first time) in a crossover design. On their first visit (week 0; baseline) participants will be asked to complete the same kind of tests that evaluated the function of their balance system at the time of their diagnosis. They will have their eye movements recorded using goggles and an infra-red camera while the prosthesis is in place and providing vibration feedback. Computerized Dynamic Posturography (CDP) testing will require them to stand on a platform and perform tests (20 seconds each) with their eyes open or closed, with the platform moving or still, and/or with the visual surround either stable or moving. They will be fitted with a safety harness that will keep them from falling. Next the investigators will evaluate their ability to perform movement tasks while walking (walking down the hall, walking down the hall avoiding objects, changing speeds while walking, going up and down stairs etc). They will walk a 25-foot distance at a comfortable gait speed, and again at a maximum gait speed. Lastly, they will be asked to fill out questionnaires. On their second and last visit, they will repeat the evaluations that were performed during the first visit.

Registry
clinicaltrials.gov
Start Date
October 1, 2017
End Date
November 30, 2018
Last Updated
5 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Ambulatory
  • Chronic imbalance for at least 1 year
  • Have reached a functional performance plateau with respect to balance performance
  • Have a DGI score of \<19
  • Fall below age and gender matched normative data for gait speed

Exclusion Criteria

  • Subjects who are unwilling or unable to adhere to all study requirements, including completion of the training period, evaluation tests, and return to clinic for a follow-up visit.
  • Women who are pregnant (women will self-report possible pregnancy).

Outcomes

Primary Outcomes

Difference in Dynamic Gait Index (DGI)

Time Frame: Week 0 (baseline)

This outcome compared the Dynamic Gait Index score when the BALCAP prosthesis was worn vs. when it was not worn at baseline in order to evaluate if there is an assistive benefit to wearing the device. The Dynamic Gait Index (DGI) is a clinical tool to assess gait, balance, and fall risk using various walking tasks. The range of scores is 0 to 24. A higher score is better. All participants performed this test at baseline both wearing the BALCAP and not wearing the BALCAP. This test does not measure a change in DGI score over time but compares the results of the test while wearing the BALCAP vs. not wearing the BALCAP during the same evaluation period (baseline).

Secondary Outcomes

  • Difference in Gait Speed(Week 0 (baseline))
  • Change in Computerized Dynamic Posturography: Equilibrium Score(Before and after 6 weeks of either the intervention or the control condition)
  • Change in Dizziness Handicap Inventory Score(Before and after 6 weeks of either the intervention or the control condition)
  • Change in Activities-specific Balance Confidence (ABC) Scale(Before and after 6 weeks of either the intervention or the control condition)

Study Sites (1)

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