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Clinical Trials/NCT06244719
NCT06244719
Recruiting
Phase 1

Vibrotactile Stimulation for Neurological Disorders

University of Colorado, Denver2 sites in 1 country24 target enrollmentFebruary 2, 2024
ConditionsStroke

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Stroke
Sponsor
University of Colorado, Denver
Enrollment
24
Locations
2
Primary Endpoint
Change in Fugl-Meyer Test of Sensorimotor Function After Stroke (UEFM)
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to investigate upper-extremity vibrotactile stimulation with wearables in stroke patients. The main questions it aims to answer are:

Are the wearables well-tolerated by patients? Does the vibrotactile stimulation help regain arm function?

Participants will wear vibrotactile stimulation gloves and shirts for 5 hours daily during their stay at the rehabilitation unit, in addition to conventional therapy. Researchers will compare the treatment group (vibrotactile stimulation wearables) with a control group (conventional therapy only) to see the effects of the vibrotactile stimulation.

Registry
clinicaltrials.gov
Start Date
February 2, 2024
End Date
February 2, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Inpatients at rehabilitation units
  • Unilateral left or right sided ischemic stroke within the previous 2 weeks
  • Have Upper-Extremity Fugl-Meyer scores between 6 and 58
  • Have at least 20 degrees of active shoulder elevation and elbow flexion
  • Expected to stay 1-3 weeks in the rehabilitation unit

Exclusion Criteria

  • Under anti-spasticity therapy
  • Patients that are dependent on pacemakers
  • Patients that have defibrillators
  • Have lymphedema or AV fistula for dialysis on an arm

Outcomes

Primary Outcomes

Change in Fugl-Meyer Test of Sensorimotor Function After Stroke (UEFM)

Time Frame: Baseline, End of the study (approximately 1-3 weeks, at discharge from the rehabilitation unit).

An impairment based measure consisting of 33 movements that tests motor and sensation of the affected arm. Higher scores indicate less impairment and more isolated motions. Scores are between 0 and 66.

Secondary Outcomes

  • Number of participants who tolerated the vibrotactile stimulation therapy(End of the study (approximately 1-3 weeks, at discharge from the rehabilitation unit).)
  • Change in the modified Ashworth scale(Baseline, End of the study (approximately 1-3 weeks, at discharge from the rehabilitation unit).)
  • Number of participants with at least one adverse event(End of the study (approximately 1-3 weeks, at discharge from the rehabilitation unit).)
  • Number of participants who completed the therapy(End of the study (approximately 1-3 weeks, at discharge from the rehabilitation unit).)

Study Sites (2)

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