Study on the interaction between remimazolam and inhaled anesthetics (sevoflurane)

Not Applicable

Recruiting

• Conditions: Patient undergoing general anesthesia and i-gel insertion

• Registration Number: JPRN-jRCT1041230104
• Lead Sponsor: Kobayashi Kensuke

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-11-10
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

1. patients who are between 40 and 60 years of age at the time of consent
2. patients scheduled for i-gel insertion for non-emergency (scheduled or temporary) surgery
3. patients with ASA (American Society of Anesthesiologists) Class I or II status
4. patients who have given their consent to this study by signing the consent form

Exclusion Criteria

1. those who are expected to have difficulty in intubation (e.g., with impaired opening, Mallampati Grade III or IV, etc.) 2.
2. patients undergoing surgery requiring intubation
3. patients with symptoms of airway infection 4. benzodiazepines or benzodiazepines
4. patients with a history of hypersensitivity to benzodiazepines or flumazenil
5. patients who should avoid sevoflurane (e.g., history of malignant hyperthermia or family history of malignant hyperthermia)
6. patients with a history of hypersensitivity to rocuronium
7. severely obese (BMI > 35)
Pregnant patients
9. nursing mothers and postpartum mothers
10. patients with the possibility of aspiration
11.Patients with a history of hypersensitivity to remimazolam
12.Patients with a history of glaucoma
13.Patients who regularly use benzodiazepines
14.Persons with psychiatric disorders
15. other patients who are judged to be exempted by the principal investigator/associate investigator

Study & Design

• Study Type: Interventional
• Study Design: Not specified